Sirtuins at iowa state, and lineage specification and western blot for selected protein
Levels of this inhibitor are high in amniotic fluid, increase towards term, and remain high in fetal blood. More advanced techniques are required to detect the PTMs in the proteins and their localization in the cell. These byproducts are seen to induce a number of autoimmune diseases like systemic sclerosis and fasciitis. Aberrations in posttranslational modifications of proteins are often observed in cancer and other diseases. Acetylation refers to addition of acetyl group in a protein.
In the biochemistry

The protein obtained by translation undergoes folding and various PTMs such as phosphorylation, alkylation, glycosylation, hydroxylation etc.
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Also, dilatation of ER could be seen in the homozygous hypomorphic embryos and the dilatation correlated with the BM abnormality, suggesting that the type IV collagen is accumulated in the ER.
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